DEF 14A of Taysha Gene Therapies, Inc., Apr 18, 2024

DEF 14A of Taysha Gene Therapies, Inc.

Filed Apr 18, 2024 · FY20230001193125-24-100792

Open on EDGAR
  1. ELECTION OF DIRECTORS

    ELECTION OF DIRECTORS Our Board of Directors is divided into three classes, and each class has a three-year term. Vacancies on the Board may be filled only by persons elected by a majority of the remaining directors. A director elected by the Board to fill a vacancy in a class, including vacancies created by an increase in the number of directors, shall serve for the remainder of the full term of that class and until the director’s successor is duly elected and qualified. The Board of Directors presently has six members. There are two directors in the class whose term of office expires in 2024. Both of the nominees listed below are currently directors of the Company. Mr. Stalfort was appointed to the Board of Directors effective June 21, 2023, to fill a vacancy created when Paul Manning resigned from the Board of Directors. Mr. Stalfort was originally identified as a potential director nominee by Sean Nolan, the Company’s Chief Executive Officer. Dr. Long was appointed to the Board of Directors effective November 1, 2023, to fill a vacancy created when Kathleen Reape resigned from the Board of Directors. Dr. Long was originally identified as a potential director nominee by Dr. Reape. If elected at the Annual Meeting, both of these nominees would serve until the 2027 Annual Meeting of Stockholders and until his or her successor has been duly elected and qualified, or, if sooner, until the director’s death, resignation or removal. It is the Company’s policy to invite and encourage directors and nominees for director to attend each Annual Meeting of Stockholders. Last year, five of our six directors then serving attended the 2023 Annual Meeting of Stockholders. Directors are elected by a plurality of the votes of the holders of shares present or represented by proxy and entitled to vote on the election of directors. Accordingly, the two nominees receiving the highest number of affirmative votes will be elected. Shares represented by executed proxies will be voted, if authority to do so is not withheld, for the election of the two nominees named below. If any nominee becomes unavailable for election as a result of an unexpected occurrence, shares that would have been voted for that nominee will instead be voted for the election of a substitute nominee proposed by Taysha. Each person nominated for election has agreed to serve if elected. The Company’s management has no reason to believe that any nominee will be unable to serve.

  2. CLASS I NOMINEES FOR ELECTION FOR A THREE-YEAR TERM EXPIRING AT THE 2027 ANNUAL MEETING

    CLASS I NOMINEES FOR ELECTION FOR A THREE-YEAR TERM EXPIRING AT THE 2027 ANNUAL MEETING The following is a brief biography of each nominee for director and a discussion of the specific experience, qualifications, attributes or skills of each nominee that led the Nominating and Corporate Governance Committee of the Board of Directors to recommend that person as a nominee for director. The Nominating and Corporate Governance Committee seeks to assemble a board that, as a whole, possesses the appropriate balance of professional and industry knowledge, financial expertise and high-level management experience necessary to oversee and direct the Company’s business. To that end, the Committee has identified and evaluated nominees in the broader context of the Board’s overall composition, with the goal of recruiting members who complement and strengthen the skills of other members and who also exhibit integrity, collegiality, sound business judgment and other qualities that the Committee views as critical to effective functioning of the Board. To provide a mix of experience and perspective on the Board, the Committee also takes into account gender, age and ethnic diversity. The brief biographies below include information, as of the date of this proxy statement, regarding the specific and particular experience, qualifications, attributes or skills of each director or nominee that led the Committee to believe that that nominee should continue to serve on the Board. Alison Long, M.D., Ph.D., age 61 Alison Long has served as a member of our Board of Directors since November 2023. She has served as the Chief Medical Officer of Flightpath Biosciences, Inc., a role she has held on a consulting basis, since January 2023, and the Clinical Lead of Enigma Biomedical Group, a role she has held on a consulting basis, since February 2023. Dr. Long previously served as Chief Medical Officer of Anokion, SA from June 2022 to January 2023. From December 2021 to April 2022, Dr. Long served as Chief Medical Officer at Kaleido Biosciences, a publicly traded biotechnology company which ceased operations in April 2022. She served as Interim Chief Medical Officer at Freeline Therapeutics, Inc., a publicly traded clinical-stage biotechnology company, from September 2021 to November 2021, and previously served as Freeline Therapeutics, Inc.’s SVP Head of Clinical Development from June 2020 to August 2021. Prior to joining Freeline Therapeutics, Inc., Dr. Long served as Head of Clinical R&D of Spark Therapeutics, Inc. from October 2019 to June 2020 and as Vice President, Clinical Development, Hemophilia of uniQure, N.V. from 2017 to October 2019. Dr. Long earned a Bachelor of Medicine, Bachelor of Surgery from the University of the Witwatersrand in Johannesburg, South Africa and a Ph.D. in Biodefense from George Mason University. Our Board believes Dr. Long is qualified to serve as a director based upon her extensive experience in research and development of several gene therapy programs. Sean Stalfort, age 54 Sean Stalfort has served as a member of our Board of Directors since June 2023. He is the President of PBM Capital Group, LLC (“PBM Capital”), a private equity and venture capital investment firm in the business of investing in healthcare and life-science related companies, which was founded in 2010. Mr. Stalfort currently serves on the boards of directors of Verrica Pharmaceuticals, Inc., a publicly-traded biopharmaceutical company, and Acumen Pharmaceuticals, Inc., a publicly-traded biopharmaceutical company. Additionally, he previously served as a member of the board of directors of Dova Pharmaceuticals, Inc., a publicly-traded biopharmaceutical company, from September 2016 to November 2019. Mr. Stalfort received a B.A. in business economics and political science from Brown University. Our Board believes Mr. Stalfort is qualified to serve as a director based on his experience in venture capital, particularly related to healthcare.

  3. CLASS I NOMINEES FOR ELECTION FOR A THREE-YEAR TERM EXPIRING AT THE 2027 ANNUAL MEETING

    | THE BOARD OF DIRECTORS RECOMMENDS A VOTE IN FAVOR OF EACH NAMED NOMINEE. |

  4. DIRECTORS CONTINUING IN OFFICE UNTIL THE 2025 ANNUAL MEETING

    DIRECTORS CONTINUING IN OFFICE UNTIL THE 2025 ANNUAL MEETING Phillip B. Donenberg, age 63 Phillip B. Donenberg has served as a member of our Board of Directors since August 2020. Mr. Donenberg served as Senior Vice President and Chief Financial Officer of Jaguar Gene Therapy, LLC, a privately held early-stage gene therapy company, from February 2020 to March 2023. Mr. Donenberg has served on the board of directors and as chairman of the audit committee of AVROBIO, Inc., a publicly traded gene therapy company, since June 2018. Previously, Mr. Donenberg served as Chief Financial Officer and Senior Vice President of Assertio Therapeutics, Inc., a pharmaceutical company, from July 2018 to November 2018. He served as Senior Vice President and Chief Financial Officer of AveXis, Inc., a publicly traded gene therapy company, from 2017 to June 2018 and as Vice President, Corporate Controller from 2016 to 2017. Mr. Donenberg earned a B.S. in accountancy from the University of Illinois Champaign-Urbana College of Business and is a Certified Public Accountant. Our Board of Directors believes that Mr. Donenberg is qualified to serve as a director based on his financial expertise and his experience as a director and executive of companies in the biotechnology and pharmaceutical industries. Sukumar Nagendran, M.D., age 58 Sukumar Nagendran has served as our President and Head of Research and Development since December 2022 and as a member of our Board of Directors since July 2020. Dr. Nagendran previously served as President, Research and Development and Chief Medical Officer at Jaguar Gene Therapy, LLC, from February 2020 to December 2022. Dr. Nagendran has served on the board of directors of Solid Biosciences Inc., a publicly traded life sciences company, since September 2018 and currently serves as an advisor to Encoded Therapeutics, Inc., a biotechnology company. He previously served on the board of directors of Health Sciences Acquisition Corp., a special purpose acquisition company, from March 2019 to December 2019 prior to its merger with Immunovant, Inc. Dr. Nagendran most recently served as Senior Vice President and Chief Medical Officer of AveXis, Inc., a publicly traded gene therapy company, from 2015 to May 2018. Dr. Nagendran earned a B.A. from Rutgers University and an M.D. from the University of Medicine and Dentistry of New Jersey and trained in Internal Medicine at Mayo Clinic in Rochester, Minnesota. Our Board of Directors believes that Dr. Nagendran is qualified to serve as a director based upon his more than 30 years of experience with gene therapy development and clinical development strategy.

  5. DIRECTORS CONTINUING IN OFFICE UNTIL THE 2026 ANNUAL MEETING

    DIRECTORS CONTINUING IN OFFICE UNTIL THE 2026 ANNUAL MEETING Sean P. Nolan, age 56 Sean P. Nolan has served as our Chief Executive Officer since December 2022 and as the Chairman of our Board of Directors since March 2020. He has served as the President of Nolan Capital, LLC, an investment fund, since October 2019. Mr. Nolan most recently served as President, Chief Executive Officer and a member of the board of directors of AveXis, Inc., a publicly traded gene therapy company, from 2015 to May 2018 until its acquisition by Novartis International AG. Mr. Nolan has served on the board of directors of Ventas, Inc., a publicly traded healthcare real estate investment trust company, since July 2019 and previously served on the board of directors of Neoleukin Therapeutics, Inc., a publicly traded biopharmaceutical company, from 2015 to June 2020.Mr. Nolan also served on the board of directors of Social Capital Suvretta Holdings Corp. II, a special purpose acquisition company, from September 2021 until July 2023. Mr. Nolan earned a B.S. in biology from John Carroll University. Our Board of Directors believes that Mr. Nolan is qualified to serve as a director based on his role as our Chief Executive Officer and his more than 30 years of broad leadership and management experience in the biopharmaceutical industry. Laura Sepp-Lorenzino, Ph.D., age 63 Laura Sepp-Lorenzino has served as a member of our Board of Directors since November 2020. She has served as Executive Vice President, Chief Scientific Officer of Intellia Therapeutics, Inc., a publicly traded biotechnology company, since May 2019. From 2017 to May 2019, Dr. Sepp-Lorenzino served as Vice President, Head of Nucleic Acid Therapies at Vertex Pharmaceuticals, Inc., a publicly traded biopharmaceutical company. She served as Vice President, Entrepreneur-in-Residence at Alnylam Pharmaceuticals, Inc., a publicly traded biopharmaceutical company, from 2014 to 2017. Dr. Sepp-Lorenzino earned a professional degree in biochemistry from the Universidad de Buenos Aires in Argentina and an M.S. and Ph.D. in biochemistry from New York University. Our Board of Directors believes that Dr. Sepp-Lorenzino is qualified to serve as a director based upon her extensive experience in research and development of nucleic acid therapies.

  6. BOARD DIVERSITY

    BOARD DIVERSITY The following Board Diversity Matrix provides the self-identified personal characteristics for our Board of Directors:

  7. BOARD DIVERSITY

    | Board Diversity Matrix (As of April 18, 2024) | | | | | | Total Number of Directors | 6 | | | | | | Female | Male | Non- Binary | Did Not Disclose Gender | | Part I: Gender Identity | | | | | | Directors | 2 | 4 | — | — | | Part II: Demographic Background | | | | | | African American or Black | — | — | — | — | | Alaskan Native or Native American | — | — | — | — | | Asian | — | 1 | — | — | | Hispanic or Latinx | — | — | — | — | | Native Hawaiian or Pacific Islander | — | — | — | — | | White | 1 | 3 | — | — | | Two or More Races or Ethnicities | 1 | — | — | — | | LGBTQ+ | — | | | | | Did Not Disclose Demographic Background | — | | | |

  8. BOARD DIVERSITY

    Our Board Diversity Matrix as of April 28, 2023 can be found in our proxy statement for the 2023 Annual Meeting filed with the SEC on May 8, 2023.

  9. INFORMATION REGARDING THE BOARD OF DIRECTORS AND CORPORATE GOVERNANCE

    INFORMATION REGARDING THE BOARD OF DIRECTORS AND CORPORATE GOVERNANCE

  10. Summary Compensation Table

    Summary Compensation Table The following table sets forth information regarding compensation awarded to, earned by and paid to our named executive officers with respect to the years ended December 31, 2023 and 2022.

  11. Summary Compensation Table

    | Name and Principal Position | Year | Salary ($) | Bonus ($) | Option Awards ($)(1) | Non-Equity Incentive Plan Compensation ($)(2) | All Other Compensation | Total | | Sean Nolan Chief Executive Officer and Director(3) | 2023 | 600,000 | — | 597,184 | 324,000 | 1,331(4) | 1,522,515 | | | 2022 | 25,000 | — | 1,800,276 | — | 74,000 | 1,899,276 | | Kamran Alam Chief Financial Officer | 2023 | 413,751 | — | 402,039 | 148,950 | 10,661(5) | 975,401 | | | 2022 | 401,700 | 156,000 | 498,215 | 136,578 | 9,330 | 1,201,823 | | Sukumar Nagendran, M.D. President and Head of Research and Development(6) | 2023 | 565,000 | — | 427,526 | 254,250 | 1,344(7) | 1,248,120 | | | 2022 | 23,542 | — | 1,285,910 | — | 54,093 | 1,363,545 |

  12. Summary Compensation Table

    | (1) This column reflects the aggregate grant date fair value of option awards granted during the year measured pursuant to ASC Topic 718, the basis for computing stock-based compensation in our financial statements. This calculation assumes that the named executive officer will perform the requisite service for the award to vest in full as required by SEC rules. The fair value of each stock option grant is estimated on the date of grant using the Black-Scholes option pricing model. The significant factors and assumptions incorporated in the Black-Scholes-Merton model used to estimate the value of the options are described in Note 2 to our consolidated financial statements included in our Annual Report on Form 10-K (File No. 001-39536) filed with the SEC on March 19, 2024. These amounts do not reflect the actual economic value that will be realized by the named executive officer upon vesting of the stock options, the exercise of the stock options or the sale of the common stock underlying such stock options. |

  13. Summary Compensation Table

    | (2) See “—Narrative to Summary Compensation Table—Non-Equity Incentive Plan Compensation” below for a description of the material terms of the program pursuant to which this compensation was awarded. |

  14. Summary Compensation Table

    | (3) Mr. Nolan’s service with us commenced in December 2022. The 2022 salary reported reflects the pro rata portion of Mr. Nolan’s annual salary of $600,000 earned during 2022 from commencement of his employment through December 31, 2022. |

  15. Summary Compensation Table

    | (4) Represents $774 in life insurance premiums for employee benefit and $557 for gift cards and associated tax gross-up payments, which we awarded to all employees in 2023 for service to our company. |

  16. Summary Compensation Table

    | (5) Represents $9,900 in Company matching contributions to benefit plans (e.g., company 401(k) matching), $270 in life insurance premiums for employee benefit and $491 for gift cards and associated tax gross-up payments, which we awarded to all employees in 2023 for service to our company. |

  17. Summary Compensation Table

    | (6) Dr. Nagendran’s service with us commenced in December 2022. The 2022 salary reported reflects the pro rata portion of Dr. Nagendran’s annual salary of $565,000 earned during 2022 from commencement of his employment through December 31, 2022. |

  18. Summary Compensation Table

    | (7) Represents $774 in life insurance premiums for employee benefit and $570 for gift cards and associated tax gross-up payments, which we awarded to all employees in 2023 for service to our company. |

  19. Outstanding Equity Awards as of December 31, 2023

    Outstanding Equity Awards as of December 31, 2023 The following table sets forth certain information about outstanding equity awards granted to our named executive officers that were outstanding as of December 31, 2023. All awards listed in the below table were granted under our 2020 Stock Incentive Plan, with the exception of the April 2020 award to Mr. Session, which was granted under our 2020 Equity Incentive Plan.

  20. Outstanding Equity Awards as of December 31, 2023

    | | | Option Awards | | | | Stock Awards | | | Name | Grant Date | Number of Securities Underlying Unexercised Options (#) Exercisable | Number of Securities Underlying Unexercised Options (#) Unexercisable | Option Exercise Price ($)(1) | Option Expiration Date | Number of Shares or Units of Stock That Have Not Vested (#) | Market Value of Shares or Units of Stock That Have Not Vested ($)(2) | | Sean Nolan | 9/23/2020 | 31,000 | — | 20.00 | 9/22/2030 | | | | | 6/17/2021 | 15,500 | — | 25.04 | 6/16/2031 | | | | | 6/17/2022 | 15,500 | — | 2.81 | 6/16/2032 | | | | | 12/30/2022 | 276,532 | 829,599(3) | 2.26 | 12/29/2032 | | | | | 12/14/2023 | — | 466,550(4) | 0.70 | 12/13/2033 | | | | Kamran Alam | 09/23/2020 | | | | | 82,781(5) | 146,522 | | | 01/19/2021 | 51,041 | 18,959(6) | 31.00 | 1/18/2031 | | | | | 02/23/2022 | 36,666 | 43,334(7) | 5.96 | 2/22/2032 | | | | | 4/6/2022 | 16,666 | 23,334(8) | 6.52 | 4/5/2032 | | | | | 2/2/2023 | — | 149,900(9) | 1.18 | 2/1/2033 | | | | | 2/2/2023 | — | 24,923(9) | 1.18 | 2/1/2023 | | | | | 2/2/2023 | | | | | 12,462(10) | 22,058 | | | 12/14/2023 | — | 187,582(4) | 0.70 | 12/13/2033 | | | | Sukumar Nagendran | 9/2/2020 | 6,979 | 1,192(11) | 14.90 | 9/2/2030 | | | | | 9/23/2020 | 31,000 | — | 20.00 | 9/23/2030 | | | | | 6/17/2021 | 15,500 | — | 25.04 | 6/16/2031 | | | | | 6/17/2022 | 15,500 | — | 2.81 | 6/16/2032 | | | | | 12/30/2022 | 197,523 | 592,570(3) | 2.26 | 12/29/2032 | | | | | 12/14/2023 | — | 334,005(4) | 0.70 | 12/13/2033 | | |

  21. Outstanding Equity Awards as of December 31, 2023

    | (1) All of the option awards listed in the table were granted with a per share exercise price equal to or above the estimated fair market value of our common stock on the date of grant. The fair market value of one share of common stock is determined to be equal to the closing price of our common stock on the Nasdaq Global Market on the date of grant (or the closing price on the last preceding date for which such quotation exists). |

  22. Outstanding Equity Awards as of December 31, 2023

    | (2) The market value of our common stock is based on the closing price of our common stock on the Nasdaq Global Market on December 31, 2023. |

  23. Outstanding Equity Awards as of December 31, 2023

    | (3) 25% of the total number of shares underlying the option shall vest and become exercisable on December 16, 2023 and the remainder shall vest and become exercisable in 36 equal monthly installments thereafter, subject to the named executive officer’s continuous service through each applicable vesting date. |

  24. Outstanding Equity Awards as of December 31, 2023

    | (4) The shares underlying the option vests and become exercisable in three equal annual installments commencing on December 31, 2024, subject to the named executive officer’s continuous service through each applicable vesting date. |

  25. Outstanding Equity Awards as of December 31, 2023

    | (5) The shares underlying the restricted stock unit vest in four equal annual installments on each of August 17, 2021, August 17, 2022, August 17, 2023 and August 17, 2024, subject to the named executive officer’s continuous service as of each such vesting date. |

  26. Outstanding Equity Awards as of December 31, 2023

    | (6) 25% of the total number of shares underlying the option vested and became exercisable on January 19, 2022 and the remainder shall vest and become exercisable in 36 equal monthly installments thereafter, subject to the named executive officer’s continuous service through each applicable vesting date. |

  27. Outstanding Equity Awards as of December 31, 2023

    | (7) 25% of the total number of shares underlying the option vested and became exercisable on February 23, 2023 and the remainder shall vest and become exercisable in 36 equal monthly installments thereafter, subject to the named executive officer’s continuous service through each applicable vesting date. |

  28. Outstanding Equity Awards as of December 31, 2023

    | (8) 25% of the total number of shares underlying the option vested and became exercisable on April 6, 2023 and the remainder shall vest and become exercisable in 36 equal monthly installments thereafter, subject to the named executive officer’s continuous service through each applicable vesting date. |

  29. Outstanding Equity Awards as of December 31, 2023

    | (9) 25% of the total number of shares underlying the option vested and became exercisable on February 2, 2024 and the remainder shall vest and become exercisable in 36 equal monthly installments thereafter, subject to the named executive officer’s continuous service through each applicable vesting date. |

  30. Outstanding Equity Awards as of December 31, 2023

    | (10) 25% of the shares underlying this restricted stock unit vested on February 2, 2024, and the remaining 75% will vest in equal installments on February 2, 2025, February 2, 2026 and February 2, 2027, subject to the named executive officer’s continuous service through each applicable vesting date. |

  31. Outstanding Equity Awards as of December 31, 2023

    | (11) 25% of the total number of shares underlying the option vested and became exercisable on July 28, 2021, with the remaining shares vesting in equal monthly installments thereafter, subject to the named executive officer’s continuous service through each applicable vesting date. |

  32. Potential Payments Upon Termination or Change in Control

    Potential Payments Upon Termination or Change in Control Each of our named executive officers is eligible to receive severance benefits under the terms of our Change in Control Severance Plan adopted by the Board of Directors in September 2020. Our Change in Control Severance Plan provides for severance benefits upon a “covered termination” that occurs during a “change in control period” (each as described below). Upon a covered termination that occurs during a change in control period, participants will be entitled to a lump sum payment equal to the participant’s base salary for a specified period (18 months for Mr. Nolan, 15 months for Dr. Nagendran and 12 months for Mr. Alam), a lump sum payment equal to a multiple of the participant’s target annual bonus (150% for Mr. Nolan and 100% for each of Dr. Nagendran and Mr. Alam), payment of continued group health benefits for a period of months (18 months for Mr. Nolan, 15 months for Dr. Nagendran and 12 months for Mr. Alam) and full accelerated vesting of all outstanding equity awards (including performance-based awards, which shall vest at 100% of target). All severance benefits under our Change in Control Severance Plan are subject to the participant’s execution of an effective release of claims against the company and compliance with the terms of any confidential information agreement, proprietary information and inventions agreement and any other agreement between the participant and the Company. For purposes of our Change in Control Severance Plan, a “covered termination” is a termination of employment by the Company without “Cause,” as defined in our Change in Control Severance Plan, or as a result of the participant’s resignation for “good reason,” as defined in our Change in Control Severance Plan, in either case, not as a result of death or disability. For purposes of our Change in Control Severance Plan, a “change in control period” is the period of time beginning on the date on which a “change in control,” as defined in the 2020 Stock Incentive Plan, becomes effective (or, in the case of Mr. Nolan and Dr. Nagendran, the period beginning three months prior to the date on which a change in control becomes effective) and ending on the first anniversary of the effective date of such change in control.

  33. DIRECTOR COMPENSATION

    DIRECTOR COMPENSATION

  34. Non-Employee Director Compensation

    Non-Employee Director Compensation The following table shows for the fiscal year ended December 31, 2023, certain information with respect to the compensation of our non-employee directors. RA Session II, our former President and Chief Executive Officer, was also a member of our Board of Directors during fiscal year 2023 but did not receive any compensation for his service as a director. See “—Separation Agreement with Mr. Session” below for a description of the compensation paid to Mr. Session in fiscal year 2023. Compensation information for Sean Nolan and Sukumar Nagendran, who did not earn any additional compensation for their service as directors during fiscal year 2023, is set forth in “Executive Compensation” above.

  35. Non-Employee Director Compensation

    | Name | Fees Earned or Paid in Cash ($) | Option Awards ($) (1)(2) | Total ($) | | Kathleen Reape, M.D. | 51,250 | 18,824 | 70,074 | | Paul B. Manning | 22,813 | — | 22,813 | | Phillip B. Donenberg | 55,000 | 18,824 | 73,824 | | Laura Sepp-Lorenzino, Ph.D. | 58,075 | 18,824 | 76,899 | | Alison Long, M.D., Ph.D. | — | 77,964 | 77,964 | | Sean Stalfort | 13,187 | 21,900 | 35,087 |

  36. Non-Employee Director Compensation

    | (1) The amounts disclosed represent the aggregate grant date fair value of the stock options granted under our 2020 Stock Incentive Plan, computed in accordance with ASC Topic 718. The fair value of each stock option grant is estimated on the date of grant using the Black-Scholes option pricing model. The significant factors and assumptions incorporated in the Black-Scholes-Merton model used to estimate the value of the options are described in Note 2 to our consolidated financial statements included in our Annual Report on Form 10-K (File No. 001-39536) filed with the SEC on March 19, 2024. This amount does not reflect the actual economic value that may be realized by such director. |

  37. Non-Employee Director Compensation

    | (2) The table below shows the aggregate number of option awards outstanding for each of our directors who is not a named executive officer, as of December 31, 2023: |

  38. Non-Employee Director Compensation

    | Name | Number of Outstanding Options | | Kathleen Reape, M.D. | 61,138 | | Paul B. Manning | — | | Phillip B. Donenberg | 106,371 | | Laura Sepp-Lorenzino, Ph.D. | 98,200 | | Alison Long, M.D., Ph.D. | 43,800 | | Sean Stalfort | 43,800 | | RA Session II* | — |

  39. Non-Employee Director Compensation

    | • | RA Session II ceased serving as our President and Chief Executive Officer in December 2022 and as a member of our Board of Directors in March 2023. |

  40. Non-Employee Director Compensation Policy

    Non-Employee Director Compensation Policy Our Board of Directors has adopted an Amended Non-Employee Director Compensation Policy (the “Amended and Restated Non-Employee Director Compensation Policy”), effective April 9, 2024, pursuant to which each of our directors who is not an employee or consultant of our company is eligible to receive compensation for service on our Board of Directors and committees of our Board of Directors. Our Compensation Committee directed Aon to develop updated recommendations regarding our non-employee director compensation policy, considering, among other factors, the Company’s peer group and the underwater status of the directors’ existing equity awards. Following an active dialogue with Aon, the Compensation Committee recommended that the Board of Directors approve Aon’s recommendations. Cash Compensation Each eligible director will receive an annual cash retainer of $35,000 for serving on our Board of Directors, and the independent chairperson of the Board of Directors will receive an additional annual cash retainer of $30,000 for his or her service. The chairperson of the Audit Committee and the chairperson of the Clinical and Scientific Committee of our Board of Directors will be entitled to an additional annual cash retainer of $15,000, the chairperson of the Compensation Committee of our Board of Directors will be entitled to an additional annual cash retainer of $10,000 and the chairperson of the Nominating and Corporate Governance Committee of our Board of Directors will be entitled to an additional annual cash retainer of $8,000. The members of the Audit Committee and the members of the Clinical and Scientific Committee of our Board of Directors will be entitled to an additional annual cash retainer of $7,500, the members of the Compensation Committee of our Board of Directors will be entitled to an additional annual cash retainer of $5,000 and the members of the Nominating and Corporate Governance Committee of our Board of Directors will be entitled to an additional annual cash retainer of $4,000; however, in each case such cash retainer is payable only to members who are not the chairperson of such committee.